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ProcessingProcessing

Int deoxyInosine

Return to Modified Bases Modifications

Historically, the first universal base employed was 2’-deoxyInosine (dI). DeoxyInosine is a naturally occurring base that, while not truly universal, is less destabilizing than mismatches involving the four standard bases. Hydrogen bond interactions between dI and dA, dG, dC and dT are weak and unequal, with the result that some base-pairing bias does exist with dI:dC > dI:dA > dI:dG > dI:dT. When present in a DNA template, deoxyInosine preferentially directs incorporation of dC in the growing nascent strand by DNA polymerase.

Scientific Details
MW:314.2
Mod Code:/ideoxyI/
Pricing Details
ProductPricingOrder
25 nmole DNA Oligo 8,00 € EUR Add To Order
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1 umole RNA Oligo 15,00 € EUR Add To Order
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1 umole DNA Plate Oligo 8,00 € EUR Add To Order
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20 nmole Ultramer® DNA Oligo 12,00 € EUR Add To Order
20 nmole Ultramer® DNA Plate Oligo 4,00 € EUR Add To Order
Structure
Structure
 
 
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