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Frequently asked questions

Our Scientific Applications Support team has assembled a list of frequently asked questions to help you find answers quickly. Filter using one or more categories to focus on specific topics, or use the search bar to perform a text search.

What is the sodium salt exchange that is done after HPLC purification?

The sodium salt exchange we perform post HPLC purification is a sodium acetate precipitation. It helps remove any remaining TEAA in the oligo preparation after HPLC purification.

It is important to make sure oligos used in vivo assays are TEAA-free because it can be toxic to cells.