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Frequently asked questions

Our Scientific Applications Support team has assembled a list of frequently asked questions to help you find answers quickly. Filter using one or more categories to focus on specific topics, or use the search bar to perform a text search.

How are the Alt-R HDR Donor Blocks modified and does IDT offer custom modifications for Alt-R HDR Donor Blocks?

Alt-R™ HDR Donor Blocks contain chemical modifications within universal, non-integrating terminal sequences to help reduce unwanted non-homologous insertion (blunt integration) events. In some cases, we can accommodate special non-catalog requests. For custom requests, you can email us directly at

*RUO—For research use only. Not for use in diagnostic procedures. Unless otherwise agreed to in writing, IDT does not intend for these products to be used in clinical applications and does not warrant their fitness or suitability for any clinical diagnostic use. Purchaser is solely responsible for all decisions regarding the use of these products and any associated regulatory or legal obligations.