The xGen® Human mtDNA Research Panel provides complete coverage of the human mitochondrial genome. The panel consists of 138 individually synthesized xGen Lockdown® Probes and delivers reliable coverage of the entire 16 kb mitochondrial genome.
The flexible, modular panel can be used as either a standalone* or spike-in panel for cost-effective and accurate detection of sequence variants in mitochondrial DNA. When added to other xGen Lockdown Panels, ranging in size from <50 kb up to the xGen Exome Research Panel, the mtDNA Research Panel does not affect the high target specificity and coverage uniformity of the original panel.
xGen Lockdown Panels and Probes for diagnostic use are also available. Contact GMPinfo@idtdna.com for more information.
* The mitochondrial genome comprises a small target space. Therefore, the xGen Human mtDNA Research Panel contains relatively few probes compared to most target capture panels. When used as a standalone panel, expect lower on-target results than when used as a spike in to a larger panel. This reduced performance is typical of small panels in hybridization capture enrichment.